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Atosiban

CAS No.: 90779-69-4
Atosiban Chemical Structure

Molecular formula:C43H67N11O12S2  

Molecular weight: 994.19 g·mol−1

Patent period: —

Dositive specifications:–

Injection :–

Oral tablets: —

Injection: —

Products are for laboratory research use only. Not for human use. We do not sell to patients.
Biological Activity

Atosiban is a peptide Oxytocin Receptor Inhibitor. Atosiban is a nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/oxytocin receptor antagonist (VOTra). Atosiban inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane. As a result, reduced release of intracellular, stored calcium from the sarcoplasmic reticulum of myometrial cells and reduced influx of Ca2+ from the extracellular space through voltage-gated channels occur. In addition, atosiban suppresses oxytocin-mediated release of PGE and PGF from the decidua.

Chemical Properties
Catalog   Num A14334
CAS NO. 90779-69-4
FORMULA C43H67N11O12S2  
M. WT 994.2
PURITY
SMILES CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSCCC(=O)N[C@@H](C(=O)N1)CC2=CC=C(C=C2)OCC)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCCN)C(=O)NCC(=O)N)CC(=O)N)[C@@H](C)O
STORAGE Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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